ARE YOU READY TO LOSE MORE?
alli IS THE ONLY FDA APPROVED OVER-THE-COUNTER WEIGHT LOSS AID
alli is the #1 doctor recommended over-the-counter weight loss aid that is clinically proven to work. Find out if alli is right for you.
alli IS THE ONLY FDA APPROVED OVER-THE-COUNTER WEIGHT LOSS AID
Dieting can feel like an uphill battle. With alli on your side, you can get a jumpstart on your diet. When used as directed, alli can help you lose 50% more weight than dieting alone.

Regular exercise

3 well-balanced meals

Plenty of water
Main benefits
As an intestinal lipase inhibitor, it blocks the absorption of approximately 25% of dietary fat, reducing calorie intake at the source. When combined with a low-fat, low-calorie diet, it enables 50% more weight loss than dieting alone. Clinical data shows that users lose an average of 2.6 kilograms more per year than those who only diet, and over 40% of users can lose 5% or more of their initial body weight — this magnitude is defined as clinically meaningful weight loss, which can reduce the risk of obesity-related diseases such as heart disease and diabetes.
- It is the only OTC weight loss aid approved by the U.S. FDA.
- It ranks first in physician recommendations among OTC weight loss products.
- It features a safe mechanism of action with no central nervous system effects.
Active Ingredient: Orlistat
- Enzyme Activity Inhibition: It binds specifically to intestinal lipase to inactivate it, preventing dietary fat from being broken down into fatty acids and monoglycerides absorbable by the human body.
- Fat Absorption Blockage: Undegraded fat cannot be absorbed by the intestinal wall and remains in the intestine in its original form.
- Natural Fat Excretion: Unabsorbed fat is excreted with feces, reducing caloric intake from fat and creating a calorie deficit when combined with a low-fat diet to achieve weight loss.
WHAT IS alli?
alli IS THE #1 DOCTOR RECOMMENDED OTC WEIGHT LOSS AID.
When used as directed, alli can help you lose 50% more weight than dieting alone.
Among over the counter (OTC) weight loss products, based on physician survey June 2021.

alli prevents about 25% of the fat you eat from getting absorbed into your body.

alli is the only FDA-approved OTC weight-loss product and the top-recommended by physicians.

alli can help you lose more than 2 inches from your waist size after 24 weeks of use.
Frequently Asked Questions
What is alli?
alli is the only FDA-approved, over-the-counter weight loss pill. Supported by a healthy diet and lifestyle, you could lose an extra pound for every two pounds you lose through diet and exercise.
Who can take alli?
alli can be taken by individuals who are 18 years old and over and are classed as overweight by a healthcare provider. Please discuss alli with your doctor before taking it.
How long does alli take to work?
If you follow a reduced-calorie, low-fat diet, take part in regular physical activity, and take alli capsules as directed, you could see results in the first two weeks. Most weight loss usually occurs within the first six months.
How does alli work?
The main active ingredient of alli is orlistat, a lipase inhibitor that works by binding itself to specific enzymes that break down fats. Through this process, 25% of consumed fat is not absorbed by the body and comes out via your digestive tract.
How effective is alli?
Since alli stops 25% fat being absorbed into the body, it reduces the calories you take in too (1 gram of fat equates to 9 calories). Along with a healthy lifestyle and diet, alli can help you lose 5-10% of your weight over time.